Dnp ( Dnp ) For Public Consumption - 1638 Words

During the First World War, the French coalition began integrating 2, 4-Dinitrophenol (DNP), as well as other nitro compounds, into their explosives.4 Since its induction, DNP has been used in several practices, ranging from wood preservation, photography development, herbicide, and dyes. In 1933, Maurice Tainter, a Stanford pharmacologist, discovered that DNP had commercial value and potency as a weight loss drug.6 Upon investigating its aromatic structure, and discovering that its interaction with cellular components was responsible for energy and heat production, Maurice was able to prove his hypothesis and confirmed that human consumption, of a previously incorporated additive in explosives and herbicides, led to substantial weight†¦show more content†¦Bachynsky was able to market his product as â€Å"Mitcal,† and converted his practice into a weight loss clinic.1 He gained much attention and publicized his drug as an integral component in his new technique called â€Å"intracellular hyperthermia therapy.† However, when several thousands of patients reported similar symptoms as the DNP crisis, and news of â€Å"Mitcal† intentional overdose, the FDA opened an investigation of Dr. Bachynsky and his practice in 1983.5 Upon further investigation, and uncovering the key component in â€Å"Mitcal† and â€Å"intracellular therapy,† Bachynsky was convicted of drug violations, penalized, and prohibited from practicing medicine or prescribing DNP to others in 1986.6 Nonetheless, this was not enough to quell Bachynsky’s dubious methods of dispensing DNP. He later evolved and discovered novel avenues to market DNP, claiming that DNP had other potent â€Å"medicine value.† Bachynsky moved his methods and practice overseas, where he fostered a marketing relationship with an establishment in Europe that was developing DNP.3 He successfully marketed his â€Å"intracellular hyperthermia therapy,† targeted to c ancer patients. However, Bachynsky was discovered and incarcerated in 2008 on fraudulent accounts.1 Since then DNP has mainly been prominent in the media, specifically in the bodybuilding and rapid weight loss avenues. There have been a plethora of case involving individuals who has attempted to take DNP, with intention of losing weight and

Depression Mental Illness And Depression - 1928 Words

Depression Overview Depression is a mental illness that has been around the world since our ancestors and is often over looked by people. Depression does not have an age requirement or personal preference; it can happen to anyone at any given time. In addition, â€Å"depression is one of the most four most common problems managed in practice† (â€Å"Physical†). Majority of the people who have depression are not treated for it. Depression is an illness because people can’t choose to act that way. There are many different factors that can tie into depression. For example, brain chemicals, genetics, physical activity, dieting, lack of sleep, poverty, and family matters. Depression has the ability to change a person’s mood at any given time. For†¦show more content†¦Another example, of a lifestyle would be products that a person chooses to buy and what products a person doesn’t choose to buy. Lifestyles are how a person is raised and how they choose or want to liv e their life. People who have depression have no control over what they are doing and what they want to do. According to the article, Depression: Major Depressive Affective Disorder depression â€Å"is a persistent low mood that interferes with the ability to function and appreciate things in life† (â€Å"Depression†). For example, a person may wake up and may not be able to do daily activities. A person may feel so mentally distressed that they may not get up for work or anything. Depression takes a toll over a person’s life, it not only effects the person it effects their family as well. If a child is raised with a depressed parent and their parent doesn’t have the proper treatment, that child may think that is the right way to act. People with depression often don’t know what to do and how to act. â€Å"It may cause a wide range of symptoms, both physical and emotional and it can last for weeks, months, or years† (â€Å"Depression† ). I believe that depression is not a lifestyle because generally people don’t want to be sad. Most people like to be happy. I don’t think anyone would choose to be sad because being sad effects everything you do for the day. For example, majority of the time when people

Epiphone Free Essays

The history of Epiphone started in 1873, in Smyrna, Ottoman Empire (now Izmir, Turkey), where Greek founder Anastasios Stathopoulos made his own fiddles and lutes (oud, laouto). Stathopoulos moved to the United States of America in 1903, and continued to make his original instruments, as well as mandolins, from Long Island City in Queens, New York. Anastasios died in 1915, and his son, Epaminondas, took over. We will write a custom essay sample on Epiphone or any similar topic only for you Order Now After two years, the company was known as The House Of Stathopoulos. Just after the end of World War I, the company started to make banjos. The company produced its Recording Line of Banjos in 1924, and, four years later, took on the name of the â€Å"Epiphone Banjo Company†. They produced their first guitars in 1928. Epi Stathopoulos died in 1943. Control of the company went to his brothers, Orphie and Frixo. Unfortunately, they were not as capable owners as Epi. In 1951, a four month long strike forced a relocation of Epiphone from New York to Philadelphia. The company was bought out by their main rival, Gibson in 1957. It is extremely important to understand that all Epiphone instruments made between 1957 and 1969 were made in the Gibson factory at 225 Parsons Street, Kalamazoo, Michigan. These 1959–1969 Epiphone instruments were, effectively, identical to the relevant Gibson versions, and made with same timber, materials and components. These guitars were made by the same people, in the same place, and with the same materials and components as the contemporary equivallent Gibson guitars were. They even shared the same Gibson serial-number sequence! To note some of the specific examples of Gibson-made Epiphone instruments from this period: the Epiphone Casino was identical to the Gibson ES-330; the Epiphone Cortez was identical to the Gibson B-25; the Epiphone Olympic Special was technically identical to the Gibson Melody Maker; the Epiphone Sorrento was identical to the Gibson ES-125TC (except for a few cosmetic improvements! ), and the Epiphone Texan was (apart from a change in scale-length) an identical guitar to the Gibson J-45. All of the other Gibson/Kalamazoo-made Epiphones had some clear technical or cosmetic relationship with the relevant Gibson version. This wealth of information can, admittedly, be quite confusing so I direct any interested readers to â€Å"Gruhn’s Guide To Vintage Guitars† (Gruhn-Carter, Miller-Freeman Press). Most of the specific information that you will need can be found here. Gibson eventually realized the folly in having two identical brands and, therefore, by 1970, Gibson commenced using the Epiphone brand as a budget-line and started having them made, initially, in Japan. Some confusion arises here because the first year or so of Japanese acoustic guitar production utilizes a label that denotes the address â€Å"Kalamzoo, MI†. At no point does this label say â€Å"Made In USA† but some confusion, especially on internet auction websites, still arises. It is equally important to understand that the overwhelming majority of Epiphone-branded instruments made since 1969 are, in essence, exploitation instruments are and are basically facsimilies of either Gibson (most commonly) or Epiphone guitars of the past. The vast majority of these facsimilies are very decent, budget-versions of the iconic instruments that they replicate and are, in may cases, exactly what a student guitarists needs, but they must not, in any way whatsoever, in terms of materials, components and intrinsic quality, be mistaken for the real item. In the hands of a good player the guitars may sound indistinguishable, but that doesn’t grant them inherent equality. [edit]Casino Main article: Epiphone Casino The most famous Epiphone model introduced by Gibson after taking over was the Casino. The Casino was made in the same shape and configuration as a Gibson ES-330 guitar. It has a very heavy sound and is a very good rhythm guitar due to its fairly thick sound when strummed. It is a genuine hollow body electric guitar with single coil P90 pickups. Epiphone Casino VT The Casino is famous for being used by The Beatles. Paul McCartney was the first to acquire one and John Lennon and George Harrison followed suit soon after. Paul McCartney used his for the solo in Taxman and the Casino sound is very prevalent throughout Revolver and their later albums. John Lennon made his Casino one of his main guitars and used it for the rest of his time with the Beatles and into the ’70s. Paul still uses his Casino, which has a Bigsby vibrato tailpiece, in concert and studio today. [edit]1970–present In the early 1970s, Epiphone began to manufacture instruments in Japan. From the 1980s, Epiphones were manufactured mainly in Korea but also in Japan by contractors licensed by Gibson. One of these contractors was Samick, which also built instruments under license for other brands and in its own name. Thus, a Korean-era solidbody Epiphone would have been built under license. The brand was primarily used to issue less expensive versions of classic Gibson models, in a manner similar to that of the Squier brand by Fender. Like all Asian-made copies, these guitars were constructed using different timbers (usually Nyatoh, for example, instead of Mahogany), were stuck together with epoxies rather than wood-glues, and were finished in hard, quick-to-apply polyester resin rather than the traditional nitro-cellulose lacquer used by Gibson. Nitro-cellulose lacquers are applied very thinly, and as a result, do not impede the resonance of the instrument as resin finishes do. Nitro-cellulose, being a solvent-based lacquer (as opposed to a catalyzed resin), requires many more very thin coats (but still results in a lighter, thinner finish because of much more hand-applied cutting and polishing) and is therefore much more time-consuming (and consequently expensive) to apply. Resin finishes are much quicker and cheaper to apply. These particular budget considerations, along with others such as plastic nuts and cheaper hardware and pickups, allow for a more affordable instrument. Although the decent Epiphone copies look (other than upon very close inspection) to be very much like the iconic, original instruments that they replicate, and often, in the hands of a good player, DO sound very, very close to the originals, they are not, as is the case with all of these budget brands, conceived and constructed to the same intrinsic quality. But it is a matter of budget – if you can look and sound close to how your favorite player sounds for a fraction of the cost then it is a good thing. Gibson, via their Epiphone brand, just like Fender via their Squier brand, bring a close approximation of the real thing to countless players who cannot afford, or justify, the expense of a professional-quality instrument. The result is that Epiphone and Squier have become the world’s highest selling brands of electric guitar. Samick has stopped manufacturing guitars in Korea. In 2002, Gibson opened a factory in Qingdao, China, which manufactures Epiphone guitars exclusively. With few exceptions, Epiphones are now built only in the Qingdao factory. Unique Epiphone models, including the Emperor, Zephyr, Riviera and Sheraton, are built to higher quality standards than the company’s â€Å"Gibson copy† line. Epiphone also produces a range of higher quality instruments under the â€Å"Elitist Series† moniker, which are built in Japan. The â€Å"Masterbilt† acoustics are manufactured in Qingdao. How to cite Epiphone, Essay examples

Epiphone Free Essays

The history of Epiphone started in 1873, in Smyrna, Ottoman Empire (now Izmir, Turkey), where Greek founder Anastasios Stathopoulos made his own fiddles and lutes (oud, laouto). Stathopoulos moved to the United States of America in 1903, and continued to make his original instruments, as well as mandolins, from Long Island City in Queens, New York. Anastasios died in 1915, and his son, Epaminondas, took over. We will write a custom essay sample on Epiphone or any similar topic only for you Order Now After two years, the company was known as The House Of Stathopoulos. Just after the end of World War I, the company started to make banjos. The company produced its Recording Line of Banjos in 1924, and, four years later, took on the name of the â€Å"Epiphone Banjo Company†. They produced their first guitars in 1928. Epi Stathopoulos died in 1943. Control of the company went to his brothers, Orphie and Frixo. Unfortunately, they were not as capable owners as Epi. In 1951, a four month long strike forced a relocation of Epiphone from New York to Philadelphia. The company was bought out by their main rival, Gibson in 1957. It is extremely important to understand that all Epiphone instruments made between 1957 and 1969 were made in the Gibson factory at 225 Parsons Street, Kalamazoo, Michigan. These 1959–1969 Epiphone instruments were, effectively, identical to the relevant Gibson versions, and made with same timber, materials and components. These guitars were made by the same people, in the same place, and with the same materials and components as the contemporary equivallent Gibson guitars were. They even shared the same Gibson serial-number sequence! To note some of the specific examples of Gibson-made Epiphone instruments from this period: the Epiphone Casino was identical to the Gibson ES-330; the Epiphone Cortez was identical to the Gibson B-25; the Epiphone Olympic Special was technically identical to the Gibson Melody Maker; the Epiphone Sorrento was identical to the Gibson ES-125TC (except for a few cosmetic improvements! ), and the Epiphone Texan was (apart from a change in scale-length) an identical guitar to the Gibson J-45. All of the other Gibson/Kalamazoo-made Epiphones had some clear technical or cosmetic relationship with the relevant Gibson version. This wealth of information can, admittedly, be quite confusing so I direct any interested readers to â€Å"Gruhn’s Guide To Vintage Guitars† (Gruhn-Carter, Miller-Freeman Press). Most of the specific information that you will need can be found here. Gibson eventually realized the folly in having two identical brands and, therefore, by 1970, Gibson commenced using the Epiphone brand as a budget-line and started having them made, initially, in Japan. Some confusion arises here because the first year or so of Japanese acoustic guitar production utilizes a label that denotes the address â€Å"Kalamzoo, MI†. At no point does this label say â€Å"Made In USA† but some confusion, especially on internet auction websites, still arises. It is equally important to understand that the overwhelming majority of Epiphone-branded instruments made since 1969 are, in essence, exploitation instruments are and are basically facsimilies of either Gibson (most commonly) or Epiphone guitars of the past. The vast majority of these facsimilies are very decent, budget-versions of the iconic instruments that they replicate and are, in may cases, exactly what a student guitarists needs, but they must not, in any way whatsoever, in terms of materials, components and intrinsic quality, be mistaken for the real item. In the hands of a good player the guitars may sound indistinguishable, but that doesn’t grant them inherent equality. [edit]Casino Main article: Epiphone Casino The most famous Epiphone model introduced by Gibson after taking over was the Casino. The Casino was made in the same shape and configuration as a Gibson ES-330 guitar. It has a very heavy sound and is a very good rhythm guitar due to its fairly thick sound when strummed. It is a genuine hollow body electric guitar with single coil P90 pickups. Epiphone Casino VT The Casino is famous for being used by The Beatles. Paul McCartney was the first to acquire one and John Lennon and George Harrison followed suit soon after. Paul McCartney used his for the solo in Taxman and the Casino sound is very prevalent throughout Revolver and their later albums. John Lennon made his Casino one of his main guitars and used it for the rest of his time with the Beatles and into the ’70s. Paul still uses his Casino, which has a Bigsby vibrato tailpiece, in concert and studio today. [edit]1970–present In the early 1970s, Epiphone began to manufacture instruments in Japan. From the 1980s, Epiphones were manufactured mainly in Korea but also in Japan by contractors licensed by Gibson. One of these contractors was Samick, which also built instruments under license for other brands and in its own name. Thus, a Korean-era solidbody Epiphone would have been built under license. The brand was primarily used to issue less expensive versions of classic Gibson models, in a manner similar to that of the Squier brand by Fender. Like all Asian-made copies, these guitars were constructed using different timbers (usually Nyatoh, for example, instead of Mahogany), were stuck together with epoxies rather than wood-glues, and were finished in hard, quick-to-apply polyester resin rather than the traditional nitro-cellulose lacquer used by Gibson. Nitro-cellulose lacquers are applied very thinly, and as a result, do not impede the resonance of the instrument as resin finishes do. Nitro-cellulose, being a solvent-based lacquer (as opposed to a catalyzed resin), requires many more very thin coats (but still results in a lighter, thinner finish because of much more hand-applied cutting and polishing) and is therefore much more time-consuming (and consequently expensive) to apply. Resin finishes are much quicker and cheaper to apply. These particular budget considerations, along with others such as plastic nuts and cheaper hardware and pickups, allow for a more affordable instrument. Although the decent Epiphone copies look (other than upon very close inspection) to be very much like the iconic, original instruments that they replicate, and often, in the hands of a good player, DO sound very, very close to the originals, they are not, as is the case with all of these budget brands, conceived and constructed to the same intrinsic quality. But it is a matter of budget – if you can look and sound close to how your favorite player sounds for a fraction of the cost then it is a good thing. Gibson, via their Epiphone brand, just like Fender via their Squier brand, bring a close approximation of the real thing to countless players who cannot afford, or justify, the expense of a professional-quality instrument. The result is that Epiphone and Squier have become the world’s highest selling brands of electric guitar. Samick has stopped manufacturing guitars in Korea. In 2002, Gibson opened a factory in Qingdao, China, which manufactures Epiphone guitars exclusively. With few exceptions, Epiphones are now built only in the Qingdao factory. Unique Epiphone models, including the Emperor, Zephyr, Riviera and Sheraton, are built to higher quality standards than the company’s â€Å"Gibson copy† line. Epiphone also produces a range of higher quality instruments under the â€Å"Elitist Series† moniker, which are built in Japan. The â€Å"Masterbilt† acoustics are manufactured in Qingdao. How to cite Epiphone, Essay examples

What Have You Been Doing Lately Essay free essay sample

, Research Paper # 8220 ; What I Have Been Doing Lately # 8221 ; is the rolling journey of a cryptic storyteller. The narrative begins with her prevarication in bed when the buzzer rings. Her province of ( un ) consciousness is non revealed. ( Does she wake up? ) The scenes of the narrative displacement within an vague and obscure clip and infinite. A narrative of approaching and traveling, return and going, the storyteller walks and walks, go forthing familiar landscapes to come in unfamiliar 1s to return to the familiar once more. The subdivisions of the narrative merge finally into a round narration, a buzzer pealing in the farewell and in the shutting lines. With an extra word, a turn of sentence construction, Kincaid differentiates the first subdivision from the 2nd and transforms the bureau of the topic. She heeds the call of the buzzer in the first subdivision by running downstairs. Quick. In the 2nd portion the action is slowed, # 8220 ; I went downstairs and opened the door but there was no 1 at that place. We will write a custom essay sample on What Have You Been Doing Lately Essay or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page In the first subdivision, she walks past the monkey, simply observing its being. In the sec ond portion, she throws several stones at it. Her inability to construct a span strands her on the shore of the big organic structure of H2O in the first subdivision, while in the 2nd subdivision, she pays a menu and rides a boat across. This tendency does non keep to be wholly true throughout the two subdivisions. Although the storyteller is much more active in the 2nd subdivision, one of the most arresting scenes in portion one is when the storyteller asks # 8220 ; what # 8217 ; s down at that place? # 8221 ; and intentionally throws herself into a hole. Not merely does she throw herself in, but she reverses herself. Tiing in with my reading of the narrative as a dream, I would place this is an illustration of limpid dreaming ; the ability to straight command, alteration, or pull strings a desirable or unwanted facet of a dream. This ability, nevertheless, is a slippery one, attesting infrequently, non normally a regular happening. At the terminal of the narrative, the storyteller is still trapped in the tintinnabulation buzzer rhythm, and is suffering. Alternatively of the unconscious resorting to clarity, she comforts herself, strokes her ain caput.

3.9 Budgeting Essays - Economy, Finance, Money, Free Essays

3.9 Budgeting Essays - Economy, Finance, Money, Free Essays 3.9 Budgeting What is a budget? A forward financial plan that covers all the aspects of a business costs and revenues (forecast) Why prepare a budget? To exercise control within a business It can provide direction and coordination To ensure that no department has an overspend Sets targets that performance can be judged against, which can motivate workers To delegate spending power to individuals or departments Budgetary Control The process by which financial control is exercise within an organization Budgets for revenue and expenditure are prepared in advance and compared with an actual performance to establish any variances Managers are held responsible for any adverse variances and will need to take action TYPES OF BUDGET Zero Budgeting Budgeted costs and revenues are set to zero Budget is based on new proposals for costs and sales Time consuming, but starting from scratch can ensure that funds are allocated the right way Historical Budgeting Use last years figures and add a little for inflation It is much quicker and simple but may not focus on problem areas of the business It does not encourage efficiency BUDGET ALLOCATION The level of expenditure will depend on the following factors: The amount available Inflation External factors This is a difficult task for certain businesses, as prices fluctuate and sales figures are unpredictable (e.g. restaurants, agriculture, and clothing company) VARIANCES - The measure of the anticipated performance (the budget) against what actually happened. The variance is the difference between the two. Favorable (positive) Variance Variance higher than expected Costs lower than expected Revenue higher than expected Budget is higher than actual Adverse (negative) Variance Variance lower than expected Costs higher than expected Revenue lower than expected Budget is lower than actual ADVANTAGES DISADVANTAGES Budgets are an efficient way to control and monitor costs Budgets are based on assumptions and are not exact Can be used as a motivational tool External factors, e.g. the economy, make it almost impossible to set accurate budgets, so could be classed as time wasting Can be used to set target and judge performance Could be demoralizing if set incorrectly Managers take short-term decision in order to meet budgetary requirements. COST AND PROFIT CENTERS COST CENTER - a section of a business, such as a department, to which all costs can be allocated or charged Examples: Manufacturing Products Factories Departments Stages in production Hotel The restaurant The reception Conference station Bar *Different businesses will use different cost centers that are appropriate to their own needs. PROFIT CENTER - a section of a business to which both costs and revenues can be allocated Examples: Each branch of a chain of shops Each department or department store In a multi-product firm, each product in the overall portfolio of the business Why do businesses divide operations into cost and profit centers? Managers and staff will have targets to work towards - if reasonable and achievable - positive impact on motivation Targets can be used to compare with actual performance and help identify those areas performing well and those not so well The individual performances of divisions and their managers can be assessed and compared Work can be monitored and decision made about the future However, Managers and workers may consider their part of the business to be more important than the whole organization Some costs - indirect costs - can be impossible to allocate to cost and profit centers accurately (arbitrary overhead allocation) Reasons for the good or bad performance of one particular profit center may be due to external factors not under its control

Dyslexia and Multisensory Teaching Approaches

Dyslexia and Multisensory Teaching Approaches Multisensory learning involves using two or more senses during the learning process. For example, a teacher who provides lots of hands-on activities, such as building a 3-dimensional map enhances their lesson by allowing the children to touch and see the concepts she is teaching. A teacher who uses oranges to teach fractions adds sight, smell, touch and taste to an otherwise difficult lesson. According to the International Dyslexia Association (IDA), multisensory teaching is an effective approach to teaching children with dyslexia. In traditional teaching, students typically use two senses: sight and hearing. Students see words when reading and they hear the teacher speaking. But many children with dyslexia may have problems processing visual and auditory information. By including more of the senses, making lessons come alive by incorporating touch, smell and taste into their lessons, teachers can reach more students and help those with dyslexia learn and retain information. Some ideas take just a little effort but can bring about big changes. Tips for Creating a Multisensory Classroom Writing homework assignments on the board. Teachers can use different colors for each subject and notations if books will be needed. For example, use yellow for math homework, red for spelling and green for history, writing a sign next to the subjects students need books or other materials. The different colors allow students to know at a glance which subjects have homework and what books to bring home.Use different colors to signify different parts of the classroom. For example, use bright colors in the main area of the classroom to help motivate children and promote creativity. Use shades of green, which help increase concentration and feelings of emotional well-being, in reading areas and computer stations.Use music in the classroom. Set math facts, spelling words or grammar rules to music, much as we use to teach children the alphabet. Use soothing music during reading time or when students are required to work quietly at their desks.Use scents in the classroom to convey differe nt feelings. According to the article Do scents affect peoples moods or work performance? in the November, 2002 issue of Scientific American, People who worked in the presence of a pleasant smelling air freshener also reported higher self-efficacy, set higher goals and were more likely to employ efficient work strategies than participants who worked in a no-odor condition. Aromatherapy can be applied to the classroom. Some common beliefs about scents include: Lavender and vanilla help promote relaxationCitrus, peppermint and pine help increase alertnessCinnamon helps to improve focus You may find that your students react differently to certain scents, so experiment to find which works best using a variety of air fresheners. Start with a picture or object. Usually, students are asked to write a story and then illustrate it, write a report, and find pictures to go with it, or draw a picture to represent a math problem. Instead, start with the picture or object. Ask students to write a story about a picture they found in a magazine or break the class into small groups and give each group a different piece of fruit, asking the group to write descriptive words or a paragraph about the fruit. Make stories come to life. Have students create skits or puppet shows to act out a story the class is reading. Have students work in small groups to act out one part of the story for the class. Use different colored paper. Instead of using plain white paper, copy hand-outs on different color paper to make the lesson more interesting. Use green paper one day, pink the next and yellow the day after. Encourage discussion. Break the class into small groups and have each group answer a different question about a story that was read. Or, have each group come up with a different ending to the story. Small groups offer each student a chance to participate in the discussion, including students with dyslexia or other learning disabilities who may be reluctant to raise their hand or speak up during class. Use different types of media to present lessons. Incorporate different ways of teaching, like films, slide shows, overhead sheets, P owerpoint presentations. Pass pictures or manipulatives around the classroom to allow students to touch and see the information up close. Making each lesson unique and interactive keeps students interest and helps them retain the information learned. Create games to review material. Create a version of Trivial Pursuit to help review facts in science or social studies. Making reviews fun and exciting will help students remember the information.   ReferencesDo scents affect peoples moods or work performance? 2002, Nov 11, Rachel S. Herz, Scientific AmericanInternational Dyslexia Association. (2001). Just the facts: Information provided by the International Dyslexia Association: Orton-Gillingham-Based and/or Multisensory Structured Language approaches. (Fact Sheet No.968). Baltimore: Maryland.