Dnp ( Dnp ) For Public Consumption - 1638 Words

During the First World War, the French coalition began integrating 2, 4-Dinitrophenol (DNP), as well as other nitro compounds, into their explosives.4 Since its induction, DNP has been used in several practices, ranging from wood preservation, photography development, herbicide, and dyes. In 1933, Maurice Tainter, a Stanford pharmacologist, discovered that DNP had commercial value and potency as a weight loss drug.6 Upon investigating its aromatic structure, and discovering that its interaction with cellular components was responsible for energy and heat production, Maurice was able to prove his hypothesis and confirmed that human consumption, of a previously incorporated additive in explosives and herbicides, led to substantial weight†¦show more content†¦Bachynsky was able to market his product as â€Å"Mitcal,† and converted his practice into a weight loss clinic.1 He gained much attention and publicized his drug as an integral component in his new technique called â€Å"intracellular hyperthermia therapy.† However, when several thousands of patients reported similar symptoms as the DNP crisis, and news of â€Å"Mitcal† intentional overdose, the FDA opened an investigation of Dr. Bachynsky and his practice in 1983.5 Upon further investigation, and uncovering the key component in â€Å"Mitcal† and â€Å"intracellular therapy,† Bachynsky was convicted of drug violations, penalized, and prohibited from practicing medicine or prescribing DNP to others in 1986.6 Nonetheless, this was not enough to quell Bachynsky’s dubious methods of dispensing DNP. He later evolved and discovered novel avenues to market DNP, claiming that DNP had other potent â€Å"medicine value.† Bachynsky moved his methods and practice overseas, where he fostered a marketing relationship with an establishment in Europe that was developing DNP.3 He successfully marketed his â€Å"intracellular hyperthermia therapy,† targeted to c ancer patients. However, Bachynsky was discovered and incarcerated in 2008 on fraudulent accounts.1 Since then DNP has mainly been prominent in the media, specifically in the bodybuilding and rapid weight loss avenues. There have been a plethora of case involving individuals who has attempted to take DNP, with intention of losing weight and

Depression Mental Illness And Depression - 1928 Words

Depression Overview Depression is a mental illness that has been around the world since our ancestors and is often over looked by people. Depression does not have an age requirement or personal preference; it can happen to anyone at any given time. In addition, â€Å"depression is one of the most four most common problems managed in practice† (â€Å"Physical†). Majority of the people who have depression are not treated for it. Depression is an illness because people can’t choose to act that way. There are many different factors that can tie into depression. For example, brain chemicals, genetics, physical activity, dieting, lack of sleep, poverty, and family matters. Depression has the ability to change a person’s mood at any given time. For†¦show more content†¦Another example, of a lifestyle would be products that a person chooses to buy and what products a person doesn’t choose to buy. Lifestyles are how a person is raised and how they choose or want to liv e their life. People who have depression have no control over what they are doing and what they want to do. According to the article, Depression: Major Depressive Affective Disorder depression â€Å"is a persistent low mood that interferes with the ability to function and appreciate things in life† (â€Å"Depression†). For example, a person may wake up and may not be able to do daily activities. A person may feel so mentally distressed that they may not get up for work or anything. Depression takes a toll over a person’s life, it not only effects the person it effects their family as well. If a child is raised with a depressed parent and their parent doesn’t have the proper treatment, that child may think that is the right way to act. People with depression often don’t know what to do and how to act. â€Å"It may cause a wide range of symptoms, both physical and emotional and it can last for weeks, months, or years† (â€Å"Depression† ). I believe that depression is not a lifestyle because generally people don’t want to be sad. Most people like to be happy. I don’t think anyone would choose to be sad because being sad effects everything you do for the day. For example, majority of the time when people

Epiphone Free Essays

The history of Epiphone started in 1873, in Smyrna, Ottoman Empire (now Izmir, Turkey), where Greek founder Anastasios Stathopoulos made his own fiddles and lutes (oud, laouto). Stathopoulos moved to the United States of America in 1903, and continued to make his original instruments, as well as mandolins, from Long Island City in Queens, New York. Anastasios died in 1915, and his son, Epaminondas, took over. We will write a custom essay sample on Epiphone or any similar topic only for you Order Now After two years, the company was known as The House Of Stathopoulos. Just after the end of World War I, the company started to make banjos. The company produced its Recording Line of Banjos in 1924, and, four years later, took on the name of the â€Å"Epiphone Banjo Company†. They produced their first guitars in 1928. Epi Stathopoulos died in 1943. Control of the company went to his brothers, Orphie and Frixo. Unfortunately, they were not as capable owners as Epi. In 1951, a four month long strike forced a relocation of Epiphone from New York to Philadelphia. The company was bought out by their main rival, Gibson in 1957. It is extremely important to understand that all Epiphone instruments made between 1957 and 1969 were made in the Gibson factory at 225 Parsons Street, Kalamazoo, Michigan. These 1959–1969 Epiphone instruments were, effectively, identical to the relevant Gibson versions, and made with same timber, materials and components. These guitars were made by the same people, in the same place, and with the same materials and components as the contemporary equivallent Gibson guitars were. They even shared the same Gibson serial-number sequence! To note some of the specific examples of Gibson-made Epiphone instruments from this period: the Epiphone Casino was identical to the Gibson ES-330; the Epiphone Cortez was identical to the Gibson B-25; the Epiphone Olympic Special was technically identical to the Gibson Melody Maker; the Epiphone Sorrento was identical to the Gibson ES-125TC (except for a few cosmetic improvements! ), and the Epiphone Texan was (apart from a change in scale-length) an identical guitar to the Gibson J-45. All of the other Gibson/Kalamazoo-made Epiphones had some clear technical or cosmetic relationship with the relevant Gibson version. This wealth of information can, admittedly, be quite confusing so I direct any interested readers to â€Å"Gruhn’s Guide To Vintage Guitars† (Gruhn-Carter, Miller-Freeman Press). Most of the specific information that you will need can be found here. Gibson eventually realized the folly in having two identical brands and, therefore, by 1970, Gibson commenced using the Epiphone brand as a budget-line and started having them made, initially, in Japan. Some confusion arises here because the first year or so of Japanese acoustic guitar production utilizes a label that denotes the address â€Å"Kalamzoo, MI†. At no point does this label say â€Å"Made In USA† but some confusion, especially on internet auction websites, still arises. It is equally important to understand that the overwhelming majority of Epiphone-branded instruments made since 1969 are, in essence, exploitation instruments are and are basically facsimilies of either Gibson (most commonly) or Epiphone guitars of the past. The vast majority of these facsimilies are very decent, budget-versions of the iconic instruments that they replicate and are, in may cases, exactly what a student guitarists needs, but they must not, in any way whatsoever, in terms of materials, components and intrinsic quality, be mistaken for the real item. In the hands of a good player the guitars may sound indistinguishable, but that doesn’t grant them inherent equality. [edit]Casino Main article: Epiphone Casino The most famous Epiphone model introduced by Gibson after taking over was the Casino. The Casino was made in the same shape and configuration as a Gibson ES-330 guitar. It has a very heavy sound and is a very good rhythm guitar due to its fairly thick sound when strummed. It is a genuine hollow body electric guitar with single coil P90 pickups. Epiphone Casino VT The Casino is famous for being used by The Beatles. Paul McCartney was the first to acquire one and John Lennon and George Harrison followed suit soon after. Paul McCartney used his for the solo in Taxman and the Casino sound is very prevalent throughout Revolver and their later albums. John Lennon made his Casino one of his main guitars and used it for the rest of his time with the Beatles and into the ’70s. Paul still uses his Casino, which has a Bigsby vibrato tailpiece, in concert and studio today. [edit]1970–present In the early 1970s, Epiphone began to manufacture instruments in Japan. From the 1980s, Epiphones were manufactured mainly in Korea but also in Japan by contractors licensed by Gibson. One of these contractors was Samick, which also built instruments under license for other brands and in its own name. Thus, a Korean-era solidbody Epiphone would have been built under license. The brand was primarily used to issue less expensive versions of classic Gibson models, in a manner similar to that of the Squier brand by Fender. Like all Asian-made copies, these guitars were constructed using different timbers (usually Nyatoh, for example, instead of Mahogany), were stuck together with epoxies rather than wood-glues, and were finished in hard, quick-to-apply polyester resin rather than the traditional nitro-cellulose lacquer used by Gibson. Nitro-cellulose lacquers are applied very thinly, and as a result, do not impede the resonance of the instrument as resin finishes do. Nitro-cellulose, being a solvent-based lacquer (as opposed to a catalyzed resin), requires many more very thin coats (but still results in a lighter, thinner finish because of much more hand-applied cutting and polishing) and is therefore much more time-consuming (and consequently expensive) to apply. Resin finishes are much quicker and cheaper to apply. These particular budget considerations, along with others such as plastic nuts and cheaper hardware and pickups, allow for a more affordable instrument. Although the decent Epiphone copies look (other than upon very close inspection) to be very much like the iconic, original instruments that they replicate, and often, in the hands of a good player, DO sound very, very close to the originals, they are not, as is the case with all of these budget brands, conceived and constructed to the same intrinsic quality. But it is a matter of budget – if you can look and sound close to how your favorite player sounds for a fraction of the cost then it is a good thing. Gibson, via their Epiphone brand, just like Fender via their Squier brand, bring a close approximation of the real thing to countless players who cannot afford, or justify, the expense of a professional-quality instrument. The result is that Epiphone and Squier have become the world’s highest selling brands of electric guitar. Samick has stopped manufacturing guitars in Korea. In 2002, Gibson opened a factory in Qingdao, China, which manufactures Epiphone guitars exclusively. With few exceptions, Epiphones are now built only in the Qingdao factory. Unique Epiphone models, including the Emperor, Zephyr, Riviera and Sheraton, are built to higher quality standards than the company’s â€Å"Gibson copy† line. Epiphone also produces a range of higher quality instruments under the â€Å"Elitist Series† moniker, which are built in Japan. The â€Å"Masterbilt† acoustics are manufactured in Qingdao. How to cite Epiphone, Essay examples

Epiphone Free Essays

The history of Epiphone started in 1873, in Smyrna, Ottoman Empire (now Izmir, Turkey), where Greek founder Anastasios Stathopoulos made his own fiddles and lutes (oud, laouto). Stathopoulos moved to the United States of America in 1903, and continued to make his original instruments, as well as mandolins, from Long Island City in Queens, New York. Anastasios died in 1915, and his son, Epaminondas, took over. We will write a custom essay sample on Epiphone or any similar topic only for you Order Now After two years, the company was known as The House Of Stathopoulos. Just after the end of World War I, the company started to make banjos. The company produced its Recording Line of Banjos in 1924, and, four years later, took on the name of the â€Å"Epiphone Banjo Company†. They produced their first guitars in 1928. Epi Stathopoulos died in 1943. Control of the company went to his brothers, Orphie and Frixo. Unfortunately, they were not as capable owners as Epi. In 1951, a four month long strike forced a relocation of Epiphone from New York to Philadelphia. The company was bought out by their main rival, Gibson in 1957. It is extremely important to understand that all Epiphone instruments made between 1957 and 1969 were made in the Gibson factory at 225 Parsons Street, Kalamazoo, Michigan. These 1959–1969 Epiphone instruments were, effectively, identical to the relevant Gibson versions, and made with same timber, materials and components. These guitars were made by the same people, in the same place, and with the same materials and components as the contemporary equivallent Gibson guitars were. They even shared the same Gibson serial-number sequence! To note some of the specific examples of Gibson-made Epiphone instruments from this period: the Epiphone Casino was identical to the Gibson ES-330; the Epiphone Cortez was identical to the Gibson B-25; the Epiphone Olympic Special was technically identical to the Gibson Melody Maker; the Epiphone Sorrento was identical to the Gibson ES-125TC (except for a few cosmetic improvements! ), and the Epiphone Texan was (apart from a change in scale-length) an identical guitar to the Gibson J-45. All of the other Gibson/Kalamazoo-made Epiphones had some clear technical or cosmetic relationship with the relevant Gibson version. This wealth of information can, admittedly, be quite confusing so I direct any interested readers to â€Å"Gruhn’s Guide To Vintage Guitars† (Gruhn-Carter, Miller-Freeman Press). Most of the specific information that you will need can be found here. Gibson eventually realized the folly in having two identical brands and, therefore, by 1970, Gibson commenced using the Epiphone brand as a budget-line and started having them made, initially, in Japan. Some confusion arises here because the first year or so of Japanese acoustic guitar production utilizes a label that denotes the address â€Å"Kalamzoo, MI†. At no point does this label say â€Å"Made In USA† but some confusion, especially on internet auction websites, still arises. It is equally important to understand that the overwhelming majority of Epiphone-branded instruments made since 1969 are, in essence, exploitation instruments are and are basically facsimilies of either Gibson (most commonly) or Epiphone guitars of the past. The vast majority of these facsimilies are very decent, budget-versions of the iconic instruments that they replicate and are, in may cases, exactly what a student guitarists needs, but they must not, in any way whatsoever, in terms of materials, components and intrinsic quality, be mistaken for the real item. In the hands of a good player the guitars may sound indistinguishable, but that doesn’t grant them inherent equality. [edit]Casino Main article: Epiphone Casino The most famous Epiphone model introduced by Gibson after taking over was the Casino. The Casino was made in the same shape and configuration as a Gibson ES-330 guitar. It has a very heavy sound and is a very good rhythm guitar due to its fairly thick sound when strummed. It is a genuine hollow body electric guitar with single coil P90 pickups. Epiphone Casino VT The Casino is famous for being used by The Beatles. Paul McCartney was the first to acquire one and John Lennon and George Harrison followed suit soon after. Paul McCartney used his for the solo in Taxman and the Casino sound is very prevalent throughout Revolver and their later albums. John Lennon made his Casino one of his main guitars and used it for the rest of his time with the Beatles and into the ’70s. Paul still uses his Casino, which has a Bigsby vibrato tailpiece, in concert and studio today. [edit]1970–present In the early 1970s, Epiphone began to manufacture instruments in Japan. From the 1980s, Epiphones were manufactured mainly in Korea but also in Japan by contractors licensed by Gibson. One of these contractors was Samick, which also built instruments under license for other brands and in its own name. Thus, a Korean-era solidbody Epiphone would have been built under license. The brand was primarily used to issue less expensive versions of classic Gibson models, in a manner similar to that of the Squier brand by Fender. Like all Asian-made copies, these guitars were constructed using different timbers (usually Nyatoh, for example, instead of Mahogany), were stuck together with epoxies rather than wood-glues, and were finished in hard, quick-to-apply polyester resin rather than the traditional nitro-cellulose lacquer used by Gibson. Nitro-cellulose lacquers are applied very thinly, and as a result, do not impede the resonance of the instrument as resin finishes do. Nitro-cellulose, being a solvent-based lacquer (as opposed to a catalyzed resin), requires many more very thin coats (but still results in a lighter, thinner finish because of much more hand-applied cutting and polishing) and is therefore much more time-consuming (and consequently expensive) to apply. Resin finishes are much quicker and cheaper to apply. These particular budget considerations, along with others such as plastic nuts and cheaper hardware and pickups, allow for a more affordable instrument. Although the decent Epiphone copies look (other than upon very close inspection) to be very much like the iconic, original instruments that they replicate, and often, in the hands of a good player, DO sound very, very close to the originals, they are not, as is the case with all of these budget brands, conceived and constructed to the same intrinsic quality. But it is a matter of budget – if you can look and sound close to how your favorite player sounds for a fraction of the cost then it is a good thing. Gibson, via their Epiphone brand, just like Fender via their Squier brand, bring a close approximation of the real thing to countless players who cannot afford, or justify, the expense of a professional-quality instrument. The result is that Epiphone and Squier have become the world’s highest selling brands of electric guitar. Samick has stopped manufacturing guitars in Korea. In 2002, Gibson opened a factory in Qingdao, China, which manufactures Epiphone guitars exclusively. With few exceptions, Epiphones are now built only in the Qingdao factory. Unique Epiphone models, including the Emperor, Zephyr, Riviera and Sheraton, are built to higher quality standards than the company’s â€Å"Gibson copy† line. Epiphone also produces a range of higher quality instruments under the â€Å"Elitist Series† moniker, which are built in Japan. The â€Å"Masterbilt† acoustics are manufactured in Qingdao. How to cite Epiphone, Essay examples